M Y Pharma

PLASMASOL is a sterile solution containing 6% Hydroxyethyl Starch (200/0.5) in isotonic Sodium Chloride solution. It is a clear, pale yellow solution.

Composition :
Each 100 ml contains: Poly (O-2-hydroxyethyl) starch INN 6.0 g, Sodium Chloride BP 0.9 g (Equals 154 mmol/L Na+ and 154 mmol/L Cl-), water for Injections BP q.s to 100 ml, Osmolarity (Theoretical) 308 mOsm/L, pH 3.5-6.0;

Indications :
PLASMASOL infusion is indicated in the treatment of hypovolaemia when plasma volume expansion is desired as an adjunct in the management of shock due to haemorrhage, surgery, sepsis, burns or other trauma. It is not a substitute for red blood cells or coagulation factors in plasma. The adjunctive use of PLASMASOL infusion in leukapheresis has also been shown to be safe and efficacious in improving the harvesting and increasing the yield of granulocytes by centrifugal means.

Dosage and administration :
PLASMASOL must be administered intravenously. Total dosage, duration and rate of infusion will depend upon the amount of blood lost and/or the haemodynamic status and general clinical condition of the patient. Dosage will need to be adjusted as necessary by monitoring the usual circulatory parameters e.g. blood pressure. The risk of circulatory overload by too rapid rate of infusion or inappropriately large doses must be borne in mind. Due to the risk for occurrence of an anaphylactic reaction, the first 10 ml - 20 ml of PLASMASOL should be infused slowly under careful observation of the patient. Maximum infusion rate: The maximum rate of infusion should be adjusted according to the clinical situation. Patients with acute haemorrhagic shock: Up to 20 ml/kg body weight/hour. In life-threatening situations: 500 ml as a rapid infusion (under pressure). The rates of infusion selected for perioperative indications and for burns and septic shock patients will usually be lowered. Maximum daily dosage : A maximum daily dosage of 2 g/kg body weight/day of Hydroxyethyl starch should not be exceeded. This corresponds to 33 ml/kg body weight/day of 6% Hydroxyethyl starch solution (approximately 2,500 ml/day in a person of 75 kg). Experience of treatment of more than 1-2 days is limited. In cases of longer treatment the daily doses have generally been lower. An increasing risk of undesirable effects with high cumulative doses should be considered. Dosage in Leukapheresis: 250 to 700 ml of PLASMASOL infusion to which citrate anticoagulant has been added is typically administered by aseptic addition to the input line of the centrifugation apparatus at a ratio of 1:8 to 1:13 to venous whole blood. The PLASMASOL infusion and citrate should be thoroughly mixed to assure effective anticoagulation of blood as it flows through the leukapheresis machine.

Use in children:
The safety and efficacy of PLASMASOL infusion in children has not been established. Administration to children should only be managed after careful benefit-risk assessment.

Fostered with enormous business understanding of this realm, we are involved in presenting a broad consignment of 3000 ML Glycine Irrigation Solutions IV Fluids Bottle.

Sodium Chloride 0.9% Irrigation Solution exerts a mechanical cleansing action for sterile irrigation of body cavities, tissues or wounds, indwelling urethral catheters and surgical drainage tubes. It also acts as diluent or vehicle for other pharmaceutical preparations

A balanced salt solution (BSS) is a solution made to a physiological pH and isotonic salt concentration. Solutions most commonly include sodium, potassium, calcium, magnesium, and chloride.Balanced salt solutions are used for washing tissues and cells and are usually combined with other agents to treat the tissues and cells. They provide the cells with water and inorganic ions, while maintaining a physiological pH and osmotic pressure.